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PIK3C2A, Active

Recombinant human PIK3C2A (299-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Catalog No. P23-112G

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Catalog No. Pack Size Price (USD)
P23-112G-05 5 ug $259
P23-112G-10 10 ug $380
P23-112G-BULK BULK Contact Us  


PIK3C2A is belongs to the phosphoinositide 3-kinase (PI3K) family which play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. PIK3C2A can phosphorylate phosphatidylinositol and phosphatidylinositol-4-phosphate in vitro (1). PIK3C2A contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases that act as calcium-dependent phospholipid binding motifs that mediate translocation of proteins to membranes, and may also mediate protein-protein interactions (2).

Gene Aliases:

PI3K-C2 (ALPHA), PI3-K-C2A, DKFZp686L193, CPK, MGC142218

Genbank Number:


1. Domin, J. et.al: Cloning of a human phosphoinositide 3-kinase with a C2 domain that displays reduced sensitivity to the inhibitor wortmannin. Biochem. J. 326: 139-147, 1997.

2. Molz, L. et.al: Cpk is a novel class of Drosophila PtdIns 3-kinase containing a C2 domain. J. Biol. Chem. 271: 13892-13899, 1996.

Specific Activity:

Sample Kinase Activity Plot. For specific information on a given lot, see related technical data sheet.


Sample Purity Data. For specific information on a given lot, see related technical data sheet.

Storage, Stability, and Shipping:

Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Molecular Weight:

155 kDa

Product Datasheets

Safety Datasheet

There are no related publications available for this product.


AKT/PKB Pathway, Angiogenesis, Apoptosis/Autophagy, Cancer, Cardiovascular Disease, Inflammation, Invasion/Metastasis, Lipid Kinases, Metabolic Disorder, Neurobiology, NfkB Pathway, WNT Signaling


  Lipid Kinase Buffer, L01-09



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