Epigenetic Enzymes

Epigenetic Enzymes

Epigenetic enzymes are crucial in maintaining key cellular functions by modifying chromatin structures and controlling gene transcription process. These reversible epigenetic DNA and histone modifications are controlled by important epigenetic enzymes such as methyltransferases and acetyltransferases. Dysregulation of these enzymes have been observed in myriad human diseases such as cancer. In recent years, epigenetic enzymes have emerged as some of the most promising classes of targets for drug discovery projects and development projects.

Scientists at SignalChem have developed a full range of epigenetic enzymes including acetyltransferases, histone deacetylases, methyltransferases and more. Our high-quality recombinant epigenetic enzymes and the assay methods are valuable tools for scientists to conduct research in epigenetics and for the pharmaceutical companies to develop novel therapeutics modulating these biological targets.

Home     >     Enzymes
Name Catalog Number
ASH2L Protein A372-30BG
COMT, Active C339-381G
DNMT1 Protein D351-31G
DNMT3A, Active D353-380G
DNMT3B, Active D353-380BG
DNMT3L, Active D353-380CG
DOT1L (KMT4), Active D344-381G
DPY30 Protein D369-30H
EED Protein E310-30H
EHMT1 (KMT1D), Active E317-381G
EHMT2, Active E318-381G
EZH1 Protein E395-30G
EZH2 (Y641C) Protein E396-32BG
EZH2 (Y641H) Protein E396-32DG
EZH2 (Y641N) Protein E396-32EG
EZH2 (Y641S) Protein E396-32FG
EZH2 Protein E396-30G
HEMK1 Protein H311-30G
KAT2A (GCN5), Active K311-381G
KAT2B (PCAF), Active K311-381BG
KAT3A (CREBBP) Protein K312-31G
KAT3A (CREBBP), Active K312-381G
KAT3B (EP300) Protein K312-31BG
KAT5 (TIP60), Active K314-380G
KAT6B (MYST4), Active K315-381BG
KAT7 (K277Q), Active K316-382AG
KAT7 (K277R), Active K316-382BG
KAT7 (MYST2), Active K316-380G
KAT8 (MYST1) Protein K317-31G
KAT9 (ELP3) Protein K318-30G
LCMT1, Active L321-380G
LCMT2 Protein L322-30G
MEP50 (WDR77) Protein W329-30G
METTL1 Protein M321-30G
METTL11A Protein M331-30G
METTL12, Active M332-30G
METTL14 Protein M334-30G
METTL16, Active M336-380G
METTL2A Protein M322-30G
METTL3 Protein M323-30G
METTL3/METTL14, Active M323-380G
MGMT Protein M354-30H
MLL1 (KMT2A), Active M341-381G
MLL2 (KMT2D), Active M342-381G
MLL3 (KMT2C), Active M343-381G
MLL5 (KMT2E), Active M345-381G
N6AMT2, Active N355-380BH
NNMT (Dog), Active N330D-380G
NNMT, Active N330-380G
PCAF Protein P09-31G
PCMT1 Protein P314-30G
PNMT (Isoform 1), Active P331D-301G
PNMT, Active P331-380G
PRDM2 (KMT8) Protein P333-31G
PRMT1, Active P365-380G
PRMT2 Protein P365-30BG
PRMT3, Active P365-380CG
PRMT4, Active P365-380DG
PRMT5 Protein P365-30EG
PRMT5/MEP50, Active P329-310EG
PRMT6, Active P365-380FG
PRMT7 Protein P365-30GG
PRMT8, Active P365-380HG
RBBP5 Protein R315-30H
SETD1A (KMT2F), Active S342-381G
SETD2 (KMT3A), Active S343-381G
SETD4 Protein S353-30G
SETD6, Active S355-380G
SETD7, Active S344-380G
SETD8 Protein S345-30G
SETDB1 (KMT1E) Protein S346-31G
SETDB2 Protein S346-30BG
SETMAR Protein S347-30G
SMYD2 (KMT3C), Active S348-380BG
SMYD3, Active S348-380CG
SUV39H1 (KMT1A), Active S350-380G
SUV39H2 (KMT1B), Active S350-380BG
SUV420H1 (KMT5B), Active S351-380G
TRDMT1 (DNMT2) Protein T352-30G
WDR5 Protein W325-30H
WHSC1 (NSD2), Active N377-381G
WHSC1L1 (NSD3) Protein N378-31G
WTAP Protein W369-30G



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