Epigenetic Enzymes

Epigenetic Enzymes

Epigenetic enzymes are crucial in maintaining key cellular functions by modifying chromatin structures and controlling gene transcription process. These reversible epigenetic DNA and histone modifications are controlled by important epigenetic enzymes such as methyltransferases and acetyltransferases. Dysregulation of these enzymes have been observed in myriad human diseases such as cancer. In recent years, epigenetic enzymes have emerged as some of the most promising classes of targets for drug discovery projects and development projects.

Scientists at SignalChem have developed a full range of epigenetic enzymes including acetyltransferases, histone deacetylases, methyltransferases and more. Our high-quality recombinant epigenetic enzymes and the assay methods are valuable tools for scientists to conduct research in epigenetics and for the pharmaceutical companies to develop novel therapeutics modulating these biological targets.

Home     >     Enzymes
Name Catalog Number
COMT, Active C339-381G
DNMT3A, Active D353-380G
DNMT3B, Active D353-380BG
DNMT3L, Active D353-380CG
DOT1L (KMT4), Active D344-381G
EHMT1 (KMT1D), Active E317-381G
EHMT2, Active E318-381G
LCMT1, Active L321-380G
MLL1 (KMT2A), Active M341-381G
MLL2 (KMT2D), Active M342-381G
MLL3 (KMT2C), Active M343-381G
MLL5 (KMT2E), Active M345-381G
N6AMT2, Active N355-380BH
NNMT (Dog), Active N330D-380G
NNMT, Active N330-380G
PNMT, Active P331-380G
PRMT1, Active P365-380G
PRMT3, Active P365-380CG
PRMT4, Active P365-380DG
PRMT6, Active P365-380FG
PRMT8, Active P365-380HG
SETD1A (KMT2F), Active S342-381G
SETD2 (KMT3A), Active S343-381G
SETD6, Active S355-380G
SETD7, Active S344-380G
SMYD2 (KMT3C), Active S348-380BG
SMYD3, Active S348-380CG
SUV39H1 (KMT1A), Active S350-380G
SUV39H2 (KMT1B), Active S350-380BG
SUV420H1 (KMT5B), Active S351-380G
WHSC1 (NSD2), Active N377-381G



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