Lipid Kinases

Lipid Kinases

Protein Kinases are a family of pivotal enzymes with 518 members implicated in various cell signaling pathways, constituting over 2% of the human genome. Kinases exert their roles by phosphorylating their respective physiological substrates. They catalyze the transfer of γ-phosphate from ATP or GTP to the hydroxyl groups of serine, threonine and tyrosine residues on the substrate proteins or the glycosyl moieties in lipids. Deregulation of Kinase could lead to the changes in enzymatic activity and/or expression, subcellular localization, the stability of kinase, protein-protein interactions. Aberrant regulation of Kinase-mediated signaling pathways is responsible for all major human pathological conditions such as cancer, cardiovascular disease, neurodegenerative diseases and metabolic disorders.

SignalChem offers a broad range of recombinant protein and lipid Kinases of superior purity and activity to assist the global academic research and drug discovery efforts with the focus on Kinases. Its active Kinase product line is one of the most comprehensive in the world in terms of the coverage and has been utilized by many pharmaceutical companies in their drug discovery programs. An in-house product development team with over 100 years of combined experience in Kinase biochemistry is behind the production and quality control of all the Kinase-related products as well as assay development.

Home     >     Enzymes
Name Catalog Number
DGKA, Active D21-10BG
DGKA, Active D21-10BH
DGKB, Active D22-10G
DGKE, Active D24-10G
DGKQ, Active D29-10G
DGKZ, Active D30-10G
PI3K (p110 alpha (E545K)/p85 alpha), Active P27-152H
PI3K (p110 alpha (N345K)/p85 alpha), Active P27-122CH
PI3K (p110 alpha(E542K)/p85) alpha, Active P27-122DH
PI3K (p110 alpha/p55 gamma), Active P27-10CG
PI3K (p110 alpha/p55 gamma), Active P27-102CH
PI3K (p110 alpha/p85 alpha), Active P27-102G
PI3K (p110 alpha/p85 alpha), Active P27-102H
PI3K (p110 alpha/p85 alpha), Active P27-182H
PI3K (p110 beta/p85 alpha), Active P28-102H
PI3K (p110 beta/p85 beta), Active P28-102BH
PI3K (p110 delta (E1021K)/p85 alpha), Active P30-122H
PI3K (p110 delta/p85 alpha), Active P30-102H
PI3K (p120 gamma), Active P29-102H
PI4K2A, Active P21-102G
PI4K2B, Active P22-102G
PI4KA, Active P31-102G
PI4KB, Active P32-102G
PIK3C2A, Active P23-112G
PIK3C2B, Active P24-112BG
PIK3C2G, Active P25-112G
PIK3C3 (Vps34), Active P26-102G
PIP4K2A, Active P76-102AG
PIP4K2B, Active P76-102BG
PIP4K2C, Active P76-102CG
PIP5K1A, Active P16-102AG
PIP5K1B, Active P16-102BG
PIP5K1C, Active P16-102CG
PIP5K3 (PIKFYVE), Active P17-112BG
SPHK1, Active S17-102G
SPHK2, Active S18-102G

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