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DPYSL2 Protein

Full-length recombinant human DPYSL2 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Catalog No. D470-30BG


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Catalog No. Pack Size Price (USD)
D470-30BG-20 20 ug $215
D470-30BG-50 50 ug $435
D470-30BG-BULK BULK Contact Us  


Overview:

Dihydropyrimidinase-related protein 2 (DPYSL2) is express-ed in both the CNS and PNS, playing a key role in neuronal development, axonal and neuronal growth, cell migration, and protein trafficking. Disruptions of DPYSL2 function have been implicated in neurodegenerative disorders such as Alzheimer's disease, neuropathic pain, and Batten disease, and to psychiatric disorders such as schizophrenia.


Gene Aliases:

CRMP2, DHPRP2, DRP-2, DRP2


Genbank Number:


References:


1. Martins-de-Souza D, et al. The protein interactome of collapsin response mediator protein-2 (CRMP2/DPYSL2) reveals novel partner proteins in brain tissue. Proteomics Clin Appl. 9: 817-31, 2015.

2. Liu Y, et al. Functional variants in DPYSL2 sequence increase risk of schizophrenia and suggest a link to mTOR signaling. G3 (Bethesda). 5:61-72, 2014.


Purity:

Sample Purity Data. For specific information on a given lot, see related technical data sheet.


Storage, Stability, and Shipping:

Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.


Molecular Weight:

~89 kDa



Product Datasheets



There are no related publications available for this product.


RESEARCH AREAS

AKT/PKB Pathway, Neurobiology



SIGNALCHEM BIOTECH INC.


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