Full-length recombinant human KAT7 (MYST2) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Catalog No. K316-380G
Catalog No. | Pack Size | Price (USD) | |
---|---|---|---|
K316-380G-05 | 5 ug | $259 | |
K316-380G-10 | 10 ug | $380 | |
K316-380G-BULK | BULK | Contact Us |
Overview:
KAT7 or K (lysine) acetyltransferase 5 is a signaling protein that belongs to the MYST family of histone acetyl transferases (HATs) and was originally isolated as an HIV-1 TAT-interactive protein which play important roles in regulating chromatin remodeling, transcription and other nuclear processes by acetylating histone and nonhistone proteins. KAT7 acts as a transcriptional inhibitor and inhibited AR-mediated transactivation of reporter constructs in CV-1 and PC-3 cells (1). KAT7 is part of a multisubunit complex that can acetylate histones H3 and H4 (2).
Gene Aliases:
MYST2; HBO1; HBOA
Genbank Number:
References:
1. Sharma, M. et.al: Androgen receptor interacts with a novel MYST protein, HBO1. J. Biol. Chem. 275: 35200-35208, 2000.
2. Iizuka, M. et.al: Histone acetyltransferase HBO1 interacts with the ORC1 subunit of the human initiator protein. J. Biol. Chem. 274: 23027-23034, 1999.
Specific Activity:
Sample Enzyme Activity Plot. For specific information on a given lot, see related technical data sheet.
Purity:
Sample Purity Data. For specific information on a given lot, see related technical data sheet.
Storage, Stability and Shipping:
Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Molecular Weight:
~110 kDa
There are no related publications available for this product.
Apoptosis/Autophagy, Cancer, Cardiovascular Disease, Cell Cycle, ERK/MAPK Pathway, Inflammation, Invasion/Metastasis, Metabolic Disorder, Neurobiology, NfkB Pathway, PKA/PKC Pathway
STAY CONNECTED
Fax: 1-604-232-4601