The CDKtide peptide sequence (CKKKYSPTSPSYSPTSPSY-SPTSPS) is derived from the C-terminus of the largest subunit of human RNA polymerase II which has 52 approximate tandem repeats of 7 amino acids Y-[ST]-P-[STQ]-[ST]-P-[SRTEVKGN]. This peptide is suitable as a substrate for CDK7, CDK8, CDK9 and CDK11.
Catalog No. C06-58
| Catalog No. | Pack Size | Price (USD) | |
|---|---|---|---|
| C06-58 | 1 mg | $83 | |
| C06-58-BULK | BULK | Contact Us |
No overview information available.
Purity:
The purity was determined to be 97.5% by HPLC analysis.
Storage, Stability and Shipping:
Store product at –20oC. For optimal storage, aliquot diluted product into smaller quantities and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Molecular Weight:
2664.94
M Kanke et al., Cohesin acetylation and Wapl-Pds5 oppositely regulate translocation of cohesin along DNA. EMBO Journal November 2016 10.15252/embj.201695756
M. Held Jason et al., Ligand Binding Promotes CDK-Dependent Phosphorylation of ER-Alpha on Hinge Serine 294 but Inhibits Ligand-Independent Phosphorylation of Serine 305 Molecular Cancer Research August 2012 10.1158/1541-7786.MCR-12-0099
Cancer, Cell Cycle, Ser/Thr Kinases
CDK3/CyclinE1, Active, C30-10G
CDK5/p35, Active, C33-10BG
CDK6/CyclinD1, Active, C35-18H
CDK4, Unactive, C31-14G
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