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GNA13 Protein

Full-length recombinant human GNA13 protein was expressed in E.coli cells using an N-terminal GST tag.
Catalog No. G118-30G


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Catalog No. Pack Size Price (USD)
G118-30G-20 20 ug $215
G118-30G-50 50 ug $435
G118-30G-BULK BULK Contact Us  


Overview:

G-alpha 13 (GNA13) is a guanine nucleotide-binding protein of the G12 class of G-alpha proteins. It activates Rho and regulates cytoplasmic as well as nuclear signaling events such as activation of the Jun N-terminal kinase signaling module, Na+/H+ exchangers, focal adhesion assemblies, and transcriptional activation of specific primary response genes. Like GNA12, GNA13 proteins are found up-regulated in several human cancers, and the GNA12/GNA13 signaling plays an important role in cancer cell invasion and metastasis.


Gene Aliases:

G13; G alpha-14


Genbank Number:


References:


1. Cheong, S. C. et al. Gene expression in human oral squamous cell carcinoma is influenced by risk factor exposure. Oral Oncol 45, 712 (2009).

2. Kelly, P. A Role for the G12 Family of Heterotrimeric G Proteins in Prostate Cancer Invasion. J Biol Chem 281, 26483 (2006).

3. http://www.phosphosite.org/proteinAction?id=2145&showAllSites=true


Purity:

Sample Purity Data. For specific information on a given lot, see related technical data sheet.


Storage, Stability, and Shipping:

Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.


Molecular Weight:

67 kDa



Product Datasheets



Safety Datasheet



There are no related publications available for this product.


RESEARCH AREAS

Angiogenesis, Apoptosis/Autophagy, Cancer


RELATED PRODUCTS


  GNA11 Protein, G116-30G

  GNA14 Protein, G119-30G

  GNAI1, Active, G121-310G

  GNAI2, Active, G122-310G


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