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ASK3, Active

Recombinant full-length human ASK3 (MAP3K15) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Catalog No. M73-10G


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Catalog No. Pack Size Price (USD)
M73-10G-05 5 ug $435
M73-10G-10 10 ug $655
M73-10G-BULK BULK Contact Us  


Overview:

ASK3 (MAP3K15) is a member of the mitogen-activated protein kinase (MAPK) family which functions in a protein kinase signal transduction cascade, where an activated MAPK kinase kinase (MAP3K) phosphorylates and activates a specific MAPK kinase (MAP2K), which then activates a specific MAPK. ASK3 plays an essential role in apoptotic cell death triggered by cellular stresses (1). ASK3 is also functions in a signal transduction pathway that is activated by various cell stresses and leads to apoptosis (2).


Gene Aliases:

MAP3K15; ASK3; bA723P2.3


Genbank Number:


References:


1. Hartz, P. A.et.al: Personal Communication. Baltimore, Md. 7/26/2010.

2. Kaji, T. et.al: ASK3, a novel member of the apoptosis signal-regulating kinase family, is essential for stress-induced cell death in HeLa cells.


Specific Activity:

Sample Activity Plot. For specific information on a given lot, see related technical data sheet.


Purity:

Sample Purity Data. For specific information on a given lot, see related technical data sheet.


Storage, Stability, and Shipping:

Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.


Molecular Weight:

180 kDa



Product Datasheets



There are no related publications available for this product.


RESEARCH AREAS

Apoptosis/Autophagy, Cancer, Cellular Stress, JNK/SAPK Pathway, p38 Pathway, Ser/Thr Kinases


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