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CDK13 (CDC2L) Protein

Recombinant human CDK13 (516-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Catalog No. C25-35G


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Catalog No. Pack Size Price (USD)
C25-35G-20 20 ug $215
C25-35G-50 50 ug $435
C25-35G-BULK BULK Contact Us  


Overview:

CDK13 or cyclin-dependent kinase 13 is a member of the cyclin-dependent serine/threonine protein kinase family which are well known for their essential roles as master switches in cell cycle control. CDK13 forms a complex with cyclin K and is predicted to play a role in gene regulation (1). CDK13 may play a role in mRNA processing and is thought to be involved in regulation of hematopoiesis (2). The CYCK-CDK12 and CYCK-CDK13 complexes display unique function in cell cycle and gene regulation.


Gene Aliases:

CDK13: CDC2L; CDC2L5; CHED; hCDK13


Genbank Number:


References:


1. Blazek, D.et.al: The cyclin K/Cdk12 complex maintains genomic stability via regulation of expression of DNA damage response genes. Genes Dev. 25: 2158-2172, 2011.

2. Lapidot-Lifson, Y.et.al: Cloning and antisense oligodeoxynucleotide inhibition of a human homolog of cdc2 required in hematopoiesis. Proc. Nat. Acad. Sci. 89: 579-583, 1992.


Purity:

Sample Purity Data. For specific information on a given lot, see related technical data sheet.


Storage, Stability and Shipping:

Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.


Molecular Weight:

~160 kDa



Product Datasheets



RESEARCH AREAS

Cancer, Cell Cycle, Ser/Thr Kinases


RELATED PRODUCTS


  CDK2/CyclinA1, Active, C29-10BG

  CDK2/CyclinA2, Active, C29-10G

  CDK5/p35, Active, C33-10BG

  CDK6/CyclinD3, Active, C35-10H


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