Home   >    Enzymes   >   Epigenetic Enzymes

KDM1B Protein

Recombinant full-length mouse KDM1B was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Catalog No. K421-30BG


Shop Online



Catalog No. Pack Size Price (USD)
K421-30BG-20 20 ug $314
K421-30BG-50 50 ug $545
K421-30BG-BULK BULK Contact Us  


Overview:

KDM1B encodes Lysine-specific histone demethylase 1B that demethylates 'Lys-4' of histone H3, a specific tag for epigenetic transcriptional activation, thereby acting as a corepressor. It specifically associates with the coding region of its target genes. Removal of endogenous KDM1B promotes an increase in H3K4me2 levels and concurrent decrease in H3K9me2 levels, with a consequent down-regulation of targeted gene transcription.


Gene Aliases:

4632428N09Rik; AI482520; Aof1


Genbank Number:


References:


1. Fang R, et al. Human LSD2/KDM1b/AOF1regulates gene transcription by modulating intragenic H3K4me2 methyla-tion. Mol Cell. 2010 Jul 30;39(2):222-33.

2. http://www.uniprot.org/uniprot/Q8NB78.


Purity:

Sample Purity Data. For specific information on a given lot, see related technical data sheet.


Storage, Stability, and Shipping:

Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.


Molecular Weight:

~118 kDa



Product Datasheets



There are no related publications available for this product.


RESEARCH AREAS

Cancer, Cell Cycle, Inflammation



SIGNALCHEM BIOTECH INC.


About

Terms of Service

Privacy Policy

Get the latest resources, updates and offers in your inbox