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p38 beta, Active

Recombinant full-length human p38β was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Catalog No. M36-10BG


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Catalog No. Pack Size Price (USD)
M36-10BG-05 5 ug $226
M36-10BG-10 10 ug $325
M36-10BG-BULK BULK Contact Us  


Overview:

p38β is a member of the p38 MAP kinase family and is activated by both proinflammatory cytokines and environmental stress (1). The p38β is activated through its phosphorylation by MAP kinase kinases (MKKs), preferably by MKK6. Transcription factor ATF2/CREB2 has been shown to be a substrate of this kinase (2). Alternatively spliced transcript variants encoding the same protein have been observed.


Gene Aliases:

MAPK11; SAPK2; p38-2; PRKM11; SAPK2B; p38b; P38b2


Genbank Number:


References:


1. Jiang, Y. et al: Characterization of the structure and function of a new mitogen-activated protein kinase (p38-beta). J. Biol. Chem. 271: 17920-17926, 1996.

2. Stein, B. et al: p38-2, a novel mitogen-activated protein kinase with distinct properties. J. Biol. Chem. 272: 19509-19517, 1997.


Specific Activity:

Sample Kinase Activity Plot. For specific information on a given lot, see related technical data sheet.


Purity:

Sample Purity Data. For specific information on a given lot, see related technical data sheet.


Storage, Stability and Shipping:

Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.


Molecular Weight:

~71 kDa



Product Datasheets



RESEARCH AREAS

Angiogenesis, Apoptosis/Autophagy, Cardiovascular Disease, Cellular Stress, Inflammation, Metabolic Disorder, Neurobiology, NfkB Pathway, p38 Pathway, Ser/Thr Kinases


RELATED PRODUCTS


  p38 alpha, Active, M39-10BG

  p38 alpha, Unactive, M39-14G

  p38 alpha, Unactive, M39-14U

  Anti-p38 alpha, M39-60M


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