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KAT7 (MYST2), Active

Full-length recombinant human KAT7 (MYST2) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Catalog No. K316-380G


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Catalog No. Pack Size Price (USD)
K316-380G-05 5 ug $259
K316-380G-10 10 ug $380
K316-380G-BULK BULK Contact Us  


Overview:

KAT7 or K (lysine) acetyltransferase 5 is a signaling protein that belongs to the MYST family of histone acetyl transferases (HATs) and was originally isolated as an HIV-1 TAT-interactive protein which play important roles in regulating chromatin remodeling, transcription and other nuclear processes by acetylating histone and nonhistone proteins. KAT7 acts as a transcriptional inhibitor and inhibited AR-mediated transactivation of reporter constructs in CV-1 and PC-3 cells (1). KAT7 is part of a multisubunit complex that can acetylate histones H3 and H4 (2).


Gene Aliases:

MYST2; HBO1; HBOA


Genbank Number:


References:


1. Sharma, M. et.al: Androgen receptor interacts with a novel MYST protein, HBO1. J. Biol. Chem. 275: 35200-35208, 2000.

2. Iizuka, M. et.al: Histone acetyltransferase HBO1 interacts with the ORC1 subunit of the human initiator protein. J. Biol. Chem. 274: 23027-23034, 1999.


Specific Activity:

Sample Enzyme Activity Plot. For specific information on a given lot, see related technical data sheet.


Purity:

Sample Purity Data. For specific information on a given lot, see related technical data sheet.


Storage, Stability and Shipping:

Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.


Molecular Weight:

~110 kDa



There are no related publications available for this product.


RESEARCH AREAS

Apoptosis/Autophagy, Cancer, Cardiovascular Disease, Cell Cycle, ERK/MAPK Pathway, Inflammation, Invasion/Metastasis, Metabolic Disorder, Neurobiology, NfkB Pathway, PKA/PKC Pathway


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  Histone H1 Protein, H10-54N

  KAT4 Protein, K313-31G


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