Recombinant full-length human Cofilin 1 was expressed in E. coli cells using an N-terminal His tag.
Catalog No. C37-54H
Catalog No. | Pack Size | Price (USD) | |
---|---|---|---|
C37-54H-20 | 20 ug | $215 | |
C37-54H-50 | 50 ug | $435 | |
C37-54H-BULK | BULK | Contact Us |
Overview:
Cofilin 1 (non-muscle), also known as CFL1, is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner (1). It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus (2). CFL1 processed proteins are most probably produced by HIV-1 protease digestion.
Gene Aliases:
CFL1, CFL
Genbank Number:
References:
1. Maciver, S.K. et al: The ADF/cofilin family: actin-remodeling proteins.". Genome Biol. 2002; 3 (5): reviews 3007.
2. Samstag, Y. Et al: Iteraction of cofilin with the serine phosphatases PP1 and PP2A in normal and neoplastic human T lymphocytes.". Adv. Enzyme Regul. 2004;97–211.
Purity:
Sample Purity Data. For specific information on a given lot, see related technical data sheet.
Storage, Stability and Shipping:
Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Molecular Weight:
~23 kDa
There are no related publications available for this product.
Cancer, Cardiovascular Disease, Invasion/Metastasis, Neurobiology
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