Recombinant full-length human MOS was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Catalog No. M57-34G
Catalog No. | Pack Size | Price (USD) | |
---|---|---|---|
M57-34G-20 | 20 ug | $215 | |
M57-34G-50 | 50 ug | $435 | |
M57-34G-BULK | BULK | Contact Us |
Overview:
MOS or v-mos Moloney murine sarcoma viral oncogene homolog is a serine/threonine kinase that activate the MAP kinase cascade through direct phosphorylation of the MAP kinase activator MEK (1). The early site-specific phosphorylation of CPEB , which was catalyzed by Eg2 is essential for the polyadenylation of c-mos mRNA, subsequent translation of c-mos, and oocyte maturation (2). The interaction with and phosphorylation of MYOD by MOS enhances muscle differentiation. MOS is an essential component of the cytostatic factor that acts almost exclusively in the second meiotic metaphase arrest.
Gene Aliases:
MGC119962; MGC119963; MSV
Genbank Number:
References:
1. Prasad, C. K. et.al: Mos 3-prime UTR regulatory differences underlie species-specific temporal patterns of Mos mRNA cytoplasmic polyadenylation and translational recruitment during oocyte maturation. Molec. Reprod. Dev. 75: 1258-1268, 2008.
2. Mendez, R. et.al: Phosphorylation of CPE binding factor by Eg2 regulates translation of c-mos mRNA. Nature 404: 302-307, 2000.
Purity:
Sample Purity Data. For specific information on a given lot, see related technical data sheet.
Storage, Stability and Shipping:
Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Molecular Weight:
~66 kDa
There are no related publications available for this product.
Cell Cycle, Ser/Thr Kinases
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