Recombinant Human MIP-4 (CCL18) was expressed in E. coli cells.
Catalog No. M844-40N
Catalog No. | Pack Size | Price (USD) | |
---|---|---|---|
M844-40N-10 | 10 ug | $185 | |
M844-40N-100 | 100 ug | $795 | |
M844-40N-BULK | BULK | Contact Us |
Overview:
CCL18, also designated dendritic cell (DC)3-derived CC chemokine 1, pulmonary and activation-regulated chemokine, alternative macrophage activation-associated CC chemokine 1, and MIP-4, is a human chemokine structurally related to CCL3. CCL18 was shown to be expressed in germinal centers of tonsils by dendritic cells and to attract mainly naive T cells, CD38 mantle zone B lymphocytes and DC. The production of CCL18 by APC is enhanced by Th2 cytokines like IL-4 and IL-13 and suppressed by IFN-gamma.
Gene Aliases:
MIP4, CCL18, Pulmonary and activation-regulated chemokine, PARC, DC-CK1, AMAC-1, C-C motif chemokine 18, Small-inducible cytokine A18, Recombinant Human Macrophage Inflammatory Protein-4 (CCL18)
Genbank Number:
Storage, Stability and Shipping:
The lyophilized protein is stable for at least one year from date of receipt at -70oC. Upon reconstitution, this cytokine can be stored in working aliquots at 2o - 8oC for one month, or at -20oC for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.
Endotoxin Level:
<1.0 EU/μg of recombinant protein as determined by the LAL method.
Molecular Weight:
8.0 kDa
Reconstitution Protocol:
A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.
Sample Cell Assay Data:
Determined by its ability to chemoattract human T cells using a concentration range of 2-40 ng/mL.
Purity:
Recombinant Human MIP-4 (CCL18) resolved on a 17% SDS-PAGE gel under reducing conditions and stained with Coomassie Brilliant Blue G-250
There are no related publications available for this product.
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