Recombinant full-length human MINDY4 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Catalog No. M534-10G
| Catalog No. | Pack Size | Price (USD) | |
|---|---|---|---|
| M534-10G-05 | 5 ug | $226 | |
| M534-10G-10 | 10 ug | $325 | |
| M534-10G-BULK | BULK | Contact Us |
Overview:
MINDY 4 is a member of motif interacting with Ub-containing novel DUB family. It is found in all eukaryotes and selectively cleaves K48-linked polyUb, a signal that targets protein degradations (1). It has been associated with teratospermina and solid tumors including colon cancer (2,3). The expression and function of MINDY4 has yet to be characterized, however it has been shown to play a role in sustaining cell survival in vitro and regulating growth in vivo. (3)
Gene Aliases:
FAM188B, C7orf67
Genbank Number:
References:
1. Abdul Rehman SA, et al: (2016) MINDY-1 is a Member of an evolutionarily conserved and structurally distinct new family of deubiquitinating enzymes. Mol Cell. 63(1):146‐155.
2. GEO Profiles: GDS2697 record.
3. Choi ES, et al: (2018) FAM188B enhances cell survival via interaction with USP7. Cell Death Dis. 9(6):633.
Activity:
Sample activity data. For lot-specific data, please refer to the lot-specific datasheet.
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Purity:
Sample purity data. for lot-specific data, please refer to the lot-specific datasheet.
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Storage, Stability, and Shipping:
Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Molecular Weight:
Approx MW 120 kDa
There are no related publications available for this product.
Cancer, Cell Cycle, Cellular Stress, Metabolic Disorder, Neurobiology
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