Recombinant full-length human FGR was expressed by baculovirus in Sf9 insect cells using a N-terminal GST tag.
Catalog No. F10-10G
Catalog No. | Pack Size | Price (USD) | |
---|---|---|---|
F10-10G-05 | 5 ug | $226 | |
F10-10G-10 | 10 ug | $325 | |
F10-10G-BULK | BULK | Contact Us |
Overview:
FGR is a protooncogene that is a unique member of the tyrosine kinase gene family. Certain lymphomas (but not sarcomas or carcinomas) express FGR-related messenger RNA. This transcript is detected in Burkitt's lymphoma cell lines naturally infected with Epstein-Barr virus (EBV), but not in EBV-negative Burkitt's lymphoma cells (1). FGR expression is limited to normal peripheral blood granulocytes, monocytes, and alveolar macrophages, all of which contain 50 to 100 copies of c-fgr mRNA per cell (2).
Gene Aliases:
SRC2; c-fgr; c-src2; FLJ43153; MGC75096; p55c-fgr; p58c-fgr
Genbank Number:
References:
1. Cheah, MS. et al: fgr proto-oncogene mRNA induced in B lymphocytes by Epstein-Barr virus infection.
Nature. 1986 Jan 16-22;319(6050):238-40..
2. Willman, CL. et al: Differential expression and regulation of the c-src and c-fgr protooncogenes in myelomonocytic cells. Proc Natl Acad Sci U S A. 1987 Jul;84(13):4480-4..
Specific Activity:
Sample Kinase Activity Plot. For specific information on a given lot, see related technical data sheet.
Purity:
Sample Purity Data. For specific information on a given lot, see related technical data sheet.
Storage, Stability and Shipping:
Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Molecular Weight:
~86kDa
There are no related publications available for this product.
Angiogenesis, Cancer, Cardiovascular Disease, Cytoplasmic Tyrosine Kinases, ERK/MAPK Pathway, Inflammation
STAY CONNECTED
Fax: 1-604-232-4601