Recombinant full-length human METTL14 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Catalog No. M334-30G
| Catalog No. | Pack Size | Price (USD) | |
|---|---|---|---|
| M334-30G-20 | 20 ug | $314 | |
| M334-30G-50 | 50 ug | $545 | |
| M334-30G-BULK | BULK | Contact Us |
Overview:
N6-adenosine-methyltransferase subunit METTL14 (Methyl-transferase-like protein 14 or METTL14) methylates adenosine residues of some mRNAs and acts as a regulator of the circadian clock and differentiation of embryonic stem cells. N6-methyladenosine (m6A), which takes place at the 5'-[AG] GAC-3' consensus sites of some mRNAs, plays a role in the efficiency of mRNA splicing, processing and mRNA stability.
Gene Aliases:
None
Genbank Number:
References:
1. http://www.uniprot.org/uniprot/Q9HCE5
2. Liu J, et al: METTL3-METTL14 complex mediates mammalian nuclear RNA N6-adenosine methylation. Nat Chem Biol. 10(2):93-5, 2014.
Purity:
Sample Purity Data. For specific information on a given lot, see related technical data sheet.
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Storage, Stability, and Shipping:
Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Molecular Weight:
~84 kDa
There are no related publications available for this product.
Neurobiology
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