The AKT (PKB) Substrate peptide sequence (CKRPRAASFAE) is based on the N-terminus of GSK3.
Catalog No. A05-58
Catalog No. | Pack Size | Price (USD) | |
---|---|---|---|
A05-58 | 1 mg | $83 | |
A05-58-BULK | BULK | Contact Us |
No overview information available.
Purity:
Determined to be 95.6% by HPLC analysis.
Storage, Stability and Shipping:
Store product at –20oC. For optimal storage, aliquot diluted product into smaller quantities and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Molecular Weight:
1235.4
Balasuriya N et al et al., Genetic code expansion and live cell imaging reveal that Thr308 phosphorylation is irreplaceable and sufficient for Akt1 activity Journal of Biological Chemistry May 2018 10.1074/jbc.RA118.002357
Zenga in et al., Lanthionine synthetase C-like protein 2 (LanCL2) is a novel regulator of Akt Molecular Biology of the Cell September 2014 10.1091/mbc.E14-01-0004
Treebak Jonas et al., Identification of a novel phosphorylation site on TBC1D4 regulated by AMP-activated protein kinase in skeletal muscle American Journal of Physiology - Cell Physiology November 2009 10.1152/ajpcell.00297.2009
Bhandaria Deepali et al., Cyclin-dependent kinase 5 activates guanine nucleotide exchange factor GIV/Girdin to orchestrate migration?proliferation dichotomy PNAS July 2015 10.1073/pnas.1514157112
Wang Yuanzhong et al., Coordinated Regulation of Serum- and Glucocorticoid-Inducible Kinase 3 by a C-terminal Hydrophobic Motif and Hsp90-Cdc37 Chaperone Complex The American Society for Biochemistry and Molecular Biology December 2013 10.1074/jbc.M113.518480
et al., Melanoma-associated mutants within the serine-rich domain of PAK5 direct kinase activity to mitogenic pathways Oncotarget May 2018
Cancer, Ser/Thr Kinases
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