Recombinant full-length human TDP43 protein was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Catalog No. T74-34G
Catalog No. | Pack Size | Price (USD) | |
---|---|---|---|
T74-34G-20 | 20 ug | $215 | |
T74-34G-50 | 50 ug | $435 | |
T74-34G-BULK | BULK | Contact Us |
Overview:
TAR DNA binding protein (TARDBP) Human was originally discovered in a screen for transcriptional repressors of the transactive response (TAR) DNA binding element of the HIV-1 virus. Contain two RNA-recognition motifs (RRM1 and RRM2), one of which partially overlaps with a putative nuclear export sequence. Mutations in TARDBP were identified in amyotrophic lateral sclerosis (ALS) patients.
Genbank Number:
References:
1. Ou SH, et al: Cloning and characterization of a novel cellular protein, TDP-43, that binds to human immunodeficiency virus type 1 TAR DNA sequence motifs. J Virol 69:3584–3596. 1995
2. Gitcho MA, et al. TDP-43 A315T mutation in familial motor neuron disease. Ann Neurol 2008 63:535–538. 2008
Alternative Name(s):
ALS10; TARDBP
Storage and Stability:
Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Purity:
Sample Purity Data. For specific information on a given lot, see related technical data sheet.
Molecular Weight:
Observed MW ~73 kDa. Calculated MW ~73 kDa.
There are no related publications available for this product.
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