Recombinant full-length human SOD1 was expressed in E. coli cells using an N-terminal GST tag.
Catalog No. S26-30G
Catalog No. | Pack Size | Price (USD) | |
---|---|---|---|
S26-30G-20 | 20 ug | $215 | |
S26-30G-50 | 50 ug | $435 | |
S26-30G-BULK | BULK | Contact Us |
Overview:
SOD1 (superoxide dismutase 1) is the major soluble cytoplasmic enzyme responsible for destroying harmful free superoxide radicals in the body thereby providing defence against oxygen free-radical toxicity. Soluble cytoplasmic SOD1 is a copper- and zinc-containing enzyme and the SOD1 gene maps to chromosome 21q22 (1). Mutations in the SOD1 gene have been implicated to be the cause of familial amyotrophic lateral sclerosis, increased age-related muscle mass loss, early development of cataracts, macular degeneration, thymic involution, hepatocellular carcinoma, and shortned lifespan (2).
Gene Aliases:
Cu/Zn-SOD, ALS, SOD, ALS1, IPOA, Homodimer, Superoxide Dismutase 1
Genbank Number:
References:
1. Sherman, L. et al: Nucleotide sequence and expression of human chromosome 21-encoded superoxide dismutase mRNA. Proc. Nat. Acad. Sci. 80: 5465-5469, 1983.
2. Al-Chalabi, Ammar, Recent advances in amyotrophic lateral sclerosis". Current Opinion in Neurology, 2000, 13 (4): 397–405.
Purity:
Sample Purity Data. For specific information on a given lot, see related technical data sheet.
Storage, Stability and Shipping:
Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Molecular Weight:
~45 kDa
There are no related publications available for this product.
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