Recombinant human KDM5C (1-671) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Catalog No. K425-31CG
Catalog No. | Pack Size | Price (USD) | |
---|---|---|---|
K425-31CG-20 | 20 ug | $215 | |
K425-31CG-50 | 50 ug | $435 | |
K425-31CG-BULK | BULK | Contact Us |
Overview:
KDM5C or lysine (K)-specific demethylase 5C is a member of the SMCY homolog family that encodes a protein with one ARID domain, one JmjC domain, one JmjN domain and two PHD-type zinc fingers. KDM5C is mainly expressed in brain and skeletal muscle. KDM5C is involved in the regulation of transcription and chromatin remodelling that cause X-linked mental retardation (1). KDM5C is also essential for spermatogenesis and expression of male-specific minor histocompatibility antigens (2).
Gene Aliases:
JARID1C; DXS1272E; MRXJ; MRXSJ; XE169
Genbank Number:
References:
1. Jensen, L. R. et.al: Mutations in the JARID1C gene, which is involved in transcriptional regulation and chromatin remodeling, cause X-linked mental retardation. Am. J. Hum. Genet. 76: 227-236, 2005.
2. Agulnik, A. I. et.al: A mouse Y chromosome gene encoded by a region essential for spermatogenesis and expression of male-specific minor histocompatibility antigens. Hum. Molec. Genet. 3: 873-878, 1994.
Purity:
Sample Purity Data. For specific information on a given lot, see related technical data sheet.
Storage, Stability and Shipping:
Store product at -70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Molecular Weight:
~118 kDa
There are no related publications available for this product.
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