Recombinant human FGFR1 (W666R) (399-end) was expressed by baculovirus in Sf9 cells using an N-terminal GST tag.
Catalog No. F04-12G
| Catalog No. | Pack Size | Price (USD) | |
|---|---|---|---|
| F04-12G-05 | 5 ug | $226 | |
| F04-12G-10 | 10 ug | $325 | |
| F04-12G-BULK | BULK | Contact Us |
Overview:
FGFR1 (also known as FLT2) is a member of the Fibroblast Growth Factor Receptor family that constitute a family of four membrane-spanning tyrosine kinases (FGFR1-4) which serve as high-affinity receptors for 17 growth factors (FGF1-17). The FGF Receptor family plays an important role in multiple biological processes, including mesoderm induction and patterning, cell growth and migration, organ formation and bone growth (1). FGFR1 is alternatively spliced generating multiple splice variants that are differentially expressed during embryo development and in the adult body (2).
Gene Aliases:
FLT2, CEK, FLG, KAL2, BFGFR, C-FGR, CD331, N-SAM
Genbank Number:
References:
1. Xu, X. et al: Fibroblast growth factor receptors (FGFRs) and their roles in limb development. Cell Tissue Res. 1999 Apr;296(1):33-43.
2. Groth, C. et al: The structure and function of vertebrate fibroblast growth factor receptor 1. Int J Dev Biol. 2002;46(4):393-400.
Activity:
Sample activity data. Please refer to the lot-specific datasheet for lot-specific information.
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Purity:
Sample purity data. for lot-specific data, please refer to the lot-specific datasheet.
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Storage, Stability, and Shipping:
Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Molecular Weight:
Approx. MW 74kDa
There are no related publications available for this product.
Angiogenesis, Apoptosis/Autophagy, Cancer, Cell Cycle, Cellular Stress, Receptor Tyrosine Kinases
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