Overview:

CAMKIβ is thought to be involved in a variety of developmental processes including development of the central nervous system (1). CAMKIβ2, an isoform of mCAMKIβ, is mainly present in the nervous system, including brain, spinal cord, trigeminal ganglion, and retina. Within the CNS, the expression of CAMKIβ2 is detected in the mantle zone suggesting its possible involvement in the differentiation of neurons (2).

Gene Aliases:

Punc; Bstk3; Camk1b; CaMKlb2; caMKlb1; Pnck

Genbank Number:

NM_012040

References:

1. Gardner,H.P. et al: Cloning, characterization, and chromosomal localization of Pnck, a Ca(2+)/calmodulin-dependent protein kinase. Genomics 63 (2), 279-288 (2000)

2. Ueda,T. et al: Distribution and intracellular localization of a mouse homologue of Ca2+/calmodulin-dependent protein kinase Ibeta2 in the nervous system. J. Neurochem. 73 (5), 2119-2129 (1999).