TAOK3, Active
Recombinant human TAOK3 (1-463) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Catalog No. T26-11G
| Catalog No. | Pack Size | Price (USD) | |
|---|---|---|---|
| T26-11G-05 | 5 ug | $226 | |
| T26-11G-10 | 10 ug | $325 | |
| T26-11G-BULK | BULK | Contact Us |
Recombinant human TAOK3 (1-463) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Catalog No. T26-11G
| Catalog No. | Pack Size | Price (USD) | |
|---|---|---|---|
| T26-11G-05 | 5 ug | $226 | |
| T26-11G-10 | 10 ug | $325 | |
| T26-11G-BULK | BULK | Contact Us |
Overview:
TAOK3 or TAO kinase 3 is a member of the serine/threonine-protein kinase family that inhibits the basal activity of Jun kinase and is negatively regulated by epidermal growth factor (EGF) (1). Overexpression of TAOK3 may activate the ERK1/ERK2 and JNK/SAPK targets. TAOK3 is highly expressed in peripheral blood leukocytes (PBLs), thymus, spleen, kidney, skeletal muscle, heart and liver (2).
Gene Aliases:
DPK, JIK, MAP3K18, FLJ31808, DKFZp666H245
Genbank Number:
References:
1. Tassi E., et al: Human JIK, a novel member of the STE20 kinase family that inhibits JNK and is negatively regulated by epidermal growth factor. J. Biol. Chem. 274:33287-33295(1999).
2. Yustein J.T.et.al: Comparative studies of a new subfamily of human Ste20-like kinases: homodimerization, subcellular localization, and selective activation of MKK3 and p38. Oncogene 22:6129-6141(2003).
Specific Activity:
Sample Kinase Activity Plot. For specific information on a given lot, see related technical data sheet.
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Purity:
Sample Purity Data. For specific information on a given lot, see related technical data sheet.
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Storage, Stability and Shipping:
Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Molecular Weight:
~89 kDa
Cancer, Inflammation, Invasion/Metastasis, JNK/SAPK Pathway, p38 Pathway, Ser/Thr Kinases
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