Recombinant human EPHA3 (571-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Catalog No. E15-11G
| Catalog No. | Pack Size | Price (USD) | |
|---|---|---|---|
| E15-11G-05 | 5 ug | $226 | |
| E15-11G-10 | 10 ug | $325 | |
| E15-11G-BULK | BULK | Contact Us |
Overview:
EPHA3 is a member of the ephrin receptor subfamily of protein-tyrosine kinases that bind the ephrin-A ligand and have diverse cellular function. Analysis of human colorectal, breast, lung and pancreatic cancer samples shows somatic mutations in the EPHA3 gene (1). EPHA3 gene expression can be regulated by CD28 and IGF-1 in Jurkat cells and expression of EPHA3 is associated with adherence and motility of malignant T cells (2).
Gene Aliases:
ETK, HEK, ETK1, HEK4, TYRO4
Genbank Number:
References:
1. Wood, L D. et al: Somatic mutations of GUCY2F, EPHA3, and NTRK3 in human cancers. Hum Mutat. 2006 Oct;27(10):1060-1.
2. Smith, L M. et al: EphA3 is induced by CD28 and IGF-1 and regulates cell adhesion. Exp Cell Res. 2004 Jan 15;292(2):295-303.
Specific Activity:
Sample Kinase Activity Plot. For specific information on a given lot, see related technical data sheet.
activity.gif)
|
Purity:
Sample Purity Data. For specific information on a given lot, see related technical data sheet.
gel.png)
|
Storage, Stability and Shipping:
Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Molecular Weight:
~72kDa
Angiogenesis, Cancer, Cardiovascular Disease, Neurobiology, Receptor Tyrosine Kinases
EPHA2, Active, E14-11G
Poly (4:1 Glu, Tyr) Peptide, P61-58
EPHA6, Active, E18-11G
EPHA1, Active, E13-18G
STAY CONNECTED
Fax: 1-604-232-4601
Toll Free: 1-866-954-6273
info@signalchem.com