Recombinant full-length human PKAcbeta was expressed by baculovirus in Sf9 insect cells using a N-terminal GST tag.
Catalog No. P52-10G
| Catalog No. | Pack Size | Price (USD) | |
|---|---|---|---|
| P52-10G-05 | 5 ug | $226 | |
| P52-10G-10 | 10 ug | $325 | |
| P52-10G-BULK | BULK | Contact Us |
Overview:
The catalytic subunit C-beta of PKA (PKAcβ) is a member of the Ser/Thr protein kinase family (the PKA catalytic subunit consist of three gene products: C-alpha, C-beta, and C-gamma) and has been assigned to human chromosome region 1p36.1 (1). PKAcβ is derived from a gene distinct from C-alpha and shows tissue-specific expression. At the amino acid level C-alpha and C-beta showed 93% homology.
Gene Aliases:
PKAb; cAPKb; MGC9320; MGC41879; DKFZp781I2452; PRKACB
Genbank Number:
References:
1. Simard, J. et al: Assignment of the gene encoding the catalytic subunit C-beta of cAMP-dependent protein kinase to the p36 band on chromosome 1. Hum. Genet. 88: 653-657, 1992.
Specific Activity:
Sample Kinase Activity Plot. For specific information on a given lot, see related technical data sheet.
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Purity:
Sample Purity Data. For specific information on a given lot, see related technical data sheet.
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Storage, Stability and Shipping:
Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Molecular Weight:
~65 kDa
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SC Stolze et al., Photo-crosslinking of clinically relevant kinases using H89-derived photo-affinity probes Molecular BioSystems May 2016 10.1039/c6mb00257a
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Apoptosis/Autophagy, Cardiovascular Disease, ERK/MAPK Pathway, Neurobiology, NfkB Pathway, PKA/PKC Pathway, Ser/Thr Kinases
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