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MAPKAPK2, Active

Recombinant human MAPKAPK2 (46-end) was expressed by baculovirus in Sf9 insect cells using a N-terminal GST tag.
Catalog No. M40-11G


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Catalog No. Pack Size Price (USD)
M40-11G-05 5 ug $226
M40-11G-10 10 ug $325
M40-11G-BULK BULK Contact Us  


Overview:

MAPKAPK2 (MAPKAP kinase2) is a Ser/Thr protein kinase which is regulated via direct phosphorylation by p38 MAP kinase (1). In conjunction with p38 MAP kinase, MAPKAPK2 is known to be involved in many cellular processes including stress and inflammatory responses, nuclear export, gene expression regulation and cell proliferation. Heat shock protein HSP27 has been shown to be one of the substrates of MAPKAPK2 in vivo.


Gene Aliases:

(2 isoforms)


Genbank Number:


References:


1. Stokoe, D. et al: The substrate specificity and structure of mitogen-activated protein (MAP) kinase-activated protein kinase-2. Biochem. J. 296: 843-849, 1993.


Specific Activity:

Sample Kinase Activity Plot. For specific information on a given lot, see related technical data sheet.


Purity:

Sample Purity Data. For specific information on a given lot, see related technical data sheet.


Storage, Stability and Shipping:

Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.


Molecular Weight:

~68 kDa



RESEARCH AREAS

Angiogenesis, Apoptosis/Autophagy, Cardiovascular Disease, Cellular Stress, Inflammation, Metabolic Disorder, Neurobiology, NfkB Pathway, p38 Pathway, Ser/Thr Kinases


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