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GNA11 Protein

Full-length recombinant human GNA11 protein was expressed in E.coli cells using an N-terminal GST tag.
Catalog No. G116-30G


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Catalog No. Pack Size Price (USD)
G116-30G-20 20 ug $215
G116-30G-50 50 ug $435
G116-30G-BULK BULK Contact Us  


Overview:

Guanine nucleotide-binding proteins (G proteins) are heterotrimeric signal-transducing molecules consisting of alpha, beta, and gamma subunits, and function as transducers downstream of G protein-coupled receptors (GPCRs) in numerous signaling cascades. The alpha subunit binds guanine nucleotide, can hydrolyze GTP, and can interact with other proteins. Guanine nucleotide-binding protein subunit alpha-11 (GNA11) acts as an activator of phospholipase C. Involved in signaling of gonadotropin-releasing hormone receptor, negatively regulating cell growth. Down-regulation may be involved in human breast cancers.


Gene Aliases:

FBH; FBH2; FHH2; GNA-11; HHC2; HYPOC2


Genbank Number:


References:


1. http://www.phosphosite.org/proteinAction?id=1101&showAllSites=true

2. http://www.uniprot.org/uniprot/P29992


Purity:

Sample Purity Data. For specific information on a given lot, see related technical data sheet.


Storage, Stability, and Shipping:

Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.


Molecular Weight:

66 kDa



Product Datasheets



Safety Datasheet



There are no related publications available for this product.


RESEARCH AREAS

Cancer, Cardiovascular Disease


RELATED PRODUCTS


  GNA14 Protein, G119-30G

  GNAI1, Active, G121-310G

  GNAI2, Active, G122-310G

  GNAI3, Active, G123-310G


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