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Vorinostat (SAHA)

HDAC Inhibitor
Catalog No. H83-904M


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Catalog No. Pack Size Price (USD)
H83-904M-50 50 mg $60
H83-904M-250 250 mg $150
H83-904M-BULK BULK Contact Us  


Overview:

Potent and selective histone deacetylase inhibitor1. Induces apoptosis in a variety of tumor cell lines2. Synergizes with kinase inhibitors to kill CNS tumor cells3. Prevents diabetes in a mouse model by immunoregulation and beta-cell protection4. Cell permeable.

References:


1. JA Vrana et al. Oncogene 1999 18:7016

2. LM Butler et al. Proc. Natl. Acad. Sci. USA 2002 99:11700

3. Y Tang et al. Cancer Biol. Ther. 2012 13:567

4. DP Christensen et al. Proc. Natl. Acad. Sci. USA 2014 111:1055


CAS Registry Number:

149647-78-9


Molecular Formula:

C14H20N2O3


Appearance:

White powder


Molecular Weight:

264.3


Purity:

>98%


Solubilization:

May be dissolved in DMSO (50 mg/ml); or Ethanol (2 mg/ml).


Aliases:

N-Hydroxy-N’-phenyloctanediamide


Storage and Stability:

Store desiccated as supplied at ambient temperature for up to 5 years. Store solutions at -20oC for up to 1 month.


Molecular Structure:



Product Datasheets



There are no related publications available for this product.


RESEARCH AREAS

Cancer, Cell Cycle, Inflammation



SIGNALCHEM BIOTECH INC.


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