JMJD Demethylase Inhibitor
Catalog No. J48-904D
| Catalog No. | Pack Size | Price (USD) | |
|---|---|---|---|
| J48-904D-5 | 5 mg | $110 | |
| J48-904D-25 | 25 mg | $425 | |
| J48-904D-BULK | BULK | Contact Us |
Overview:
Inhibits the JMJD family of 2-oxoglutarate-dependent histone demethylases. IC50 = 0.12, 0.07, 0.2, 0.3, 0.6, and 1 μM for JMJD3, JMJD1A, JMJD2A, JMJD2E, JMJD2C and UTX respectively1. A broad spectrum 2-oxoglutarate oxygenase inhibitor which may be used to study hypoxic signaling1. Cell permeable
References:
1. ON King et al. PLoS One 2010 5:e15535
CAS Registry Number:
5852-78-8
Molecular Formula:
C10H7NO3
Appearance:
Yellow powder
Molecular Weight:
189.2
Purity:
>98% (HPLC)
Solubilization:
May be dissolved in DMSO (20 mg/ml)
Aliases:
5-Carboxy-8-hydroxyquinoline, 8-Hydroxy-5-quinolinecarboxylic acid
Storage and Stability:
Store desiccated as supplied at ambient temperature for up to 1 year. Store solutions at -20oC for up to 3 months.
Molecular Structure:
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There are no related publications available for this product.
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