HAT Inhibitor
Catalog No. K311-903C
| Catalog No. | Pack Size | Price (USD) | |
|---|---|---|---|
| K311-903C-10 | 10 mg | $105 | |
| K311-903C-50 | 50 mg | $420 | |
| K311-903C-BULK | BULK | Contact Us |
Overview:
Potent inhibitor of histone acetyl transferases p300 (IC50=7 uM) and pCAF (IC50=5 uM)1. Induces apoptosis in various cell lines2. Promotes expansion of human hematopoietic stem cells3. Cell permeable.
References:
1. K Balasubramanyam et al. J. Biol. Chem. 2004 279:33716
2. MA Parasramka et al. Nutr. Cancer 2011 63:456
3. T Nishino et al. Nutr. PLoS One 2011 6:e24298
CAS Registry Number:
78824-30-3
Molecular Formula:
C38H50O6
Appearance:
Yellow powder
Molecular Weight:
602.8
Purity:
>97% (TLC)
Solubilization:
May be dissolved in DMSO (25 mg/ml); or ethanol (25 mg/ml)
Aliases:
Camboginol, 3-(3,4-dihydroxybenzoyl)-4-hydroxy-8,8-dimethyl-1,7-bis(3-methyl-2-buten-1-yl)-5-[(2S)-5-methyl-2-(1-methylethenyl)-4-hexen-1-yl]-bicyclo[3.3.1]non-3-ene-2,9-dione
Storage and Stability:
Store desiccated as supplied at -20oC for up to 2 years. Store solutions at -20oC for up to 2 months.
Molecular Structure:
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There are no related publications available for this product.
Apoptosis/Autophagy, Cancer, Cardiovascular Disease, Cell Cycle, ERK/MAPK Pathway, Inflammation, Invasion/Metastasis, Metabolic Disorder, Neurobiology, NfkB Pathway, PKA/PKC Pathway
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