Inhibits Jumonji C Domain Containing Proteins
Catalog No. J48-904
Catalog No. | Pack Size | Price (USD) | |
---|---|---|---|
J48-904-50 | 50 mg | $90 | |
J48-904-100 | 100 mg | $165 | |
J48-904-BULK | BULK | Contact Us |
Overview:
Inhibits PHD or prolyl hydroxylase domain-containing proteins, activating HIF1α
References:
1. TM Asikainen et al. Proc. Natl. Acad. Sci. USA 2005 102:10212
2. P Jaakkola et al. Science 2001 292:468
3. S. Hamada et al. Bioorg. Med. Chem. Lett. 2009 19:2852
4. DJ Lomb et al. Mol. Pharmacol. 2009 75:1198
5. L Xie et al. J. Clin. Invest. 2012 122:2827
CAS Registry Number:
89464-63-1
Molecular Formula:
C6H9NO5
Appearance:
White to off-white solid
Melting Point:
46-48oC
Molecular Weight:
175.1
Purity:
>98%
Solubilization:
May be dissolved in DMSO (30 mg/ml), ethanol (25 mg/ml), or water (30 mg/ml)
Aliases:
N-(2-Methoxy-2-oxoacetyl)glycine methyl ester; Dimethyloxalylglycine
Storage and Stability:
Store desiccated as supplied at -20oC for up to 2 years. Store solutions at -20oC for up to 1 month.
Molecular Structure:
There are no related publications available for this product.
Cancer, Cell Cycle, Inflammation
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