Recombinant human NEK5 (1-508) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Catalog No. N07-11G
Catalog No. | Pack Size | Price (USD) | |
---|---|---|---|
N07-11G-05 | 5 ug | $226 | |
N07-11G-10 | 10 ug | $325 | |
N07-11G-BULK | BULK | Contact Us |
Overview:
NEK5 or NIMA (never in mitosis gene a)-related kinase 5 is a serine/threonine kinase that is involved in cell cycle regulation. NEK5 has been shown to interact with NEK6 and NEK5 are required for the ibo1/nek6 ectopic outgrowth phenotype in epidermal cells (1). NEK6 interacts and co-localizes with NEK5 in a transient expression assay. The ibo1-3 mutation markedly increases the interaction between NEK6 and NEK5. NEK6 forms heterodimers with NEK5 to regulate cortical microtubule organization possibly through the phosphorylation of β-tubulins. The NEK5 gene is conserved in chimpanzee, cow, mouse, rat, and chicken.
Gene Aliases:
MGC75495
Genbank Number:
References:
1. Motose, H. et al: NIMA-related kinases 6, 4, and 5 interact with each other to regulate microtubule organization during epidermal cell expansion in Arabidopsis thaliana. Plant J. 2011 Sep;67(6):993-1005.
Specific Activity:
Sample Kinase Activity Plot. For specific information on a given lot, see related technical data sheet.
Purity:
Sample Purity Data. For specific information on a given lot, see related technical data sheet.
Storage, Stability and Shipping:
Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Molecular Weight:
~84 kDa
There are no related publications available for this product.
Cancer, Cell Cycle, Ser/Thr Kinases
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