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AATK Protein

Recombinant mouse AATK (8-411) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Catalog No. A02-35G


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Catalog No. Pack Size Price (USD)
A02-35G-20 20 ug $215
A02-35G-50 50 ug $435
A02-35G-BULK BULK Contact Us  


Overview:

AATK or apoptosis-associated tyrosine kinase contains a tyrosine kinase domain at the N-terminus and a proline-rich domain at the C-terminus. AATK is induced during apoptosis, and expression of this protein is a necessary pre-requisite for the induction of growth arrest and/or apoptosis of myeloid precursor cells (1). AATK is highly detected in brain, lung, kidney, and pancreas (2). AATK is also shown to produce neuronal differentiation in a neuroblastoma cell line.


Gene Aliases:

AATYK; LMTK1; KIAA0641


Genbank Number:


References:


1. Gaozza, E. et.al: AATYK: a novel tyrosine kinase induced during growth arrest and apoptosis of myeloid cells. Oncogene 15: 3127-3135, 1997.

2. Ishikawa, K. et.al: Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. DNA Res. 5: 169-176, 1998.


Purity:

Sample Purity Data. For specific information on a given lot, see related technical data sheet.


Storage, Stability and Shipping:

Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.


Molecular Weight:

~71 kDa



Product Datasheets



There are no related publications available for this product.


RESEARCH AREAS

Apoptosis/Autophagy, Cancer, Cytoplasmic Tyrosine Kinases



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