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PXK Protein

Full-length recombinant human PXK was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Catalog No. P99-35G


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Catalog No. Pack Size Price (USD)
P99-35G-20 20 ug $215
P99-35G-50 50 ug $435
P99-35G-BULK BULK Contact Us  


Overview:

PX Domain Containing Serine/Threonine Kinase (PXK) is involved in synaptic transmission through modulating brain Na,K-ATPase subunits ATP1B1 and ATP1B3 participate in the ligand-induced internalization and degradation of epidermal growth factors. Mutation of this gene may be associated with susceptibility to systemic lupus erythematosus (SLE).


Gene Aliases:

FLJ20335; MONaKA


Genbank Number:


References:


1. Takeuchi H, et al. Characterization of PXK as a protein involved in epidermal growth factor receptor trafficking. Mol Cell Biol. 30:1689-702, 2010.

2. Zou X, et al. Expression pattern and subcellular localization of five splice isoforms of human PXK. Int J Mol Med. 16:701-7, 2005 Oct.


Purity:

Sample Purity Data. For specific information on a given lot, see related technical data sheet.


Storage, Stability, and Shipping:

Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.


Molecular Weight:

~90 kDa



Product Datasheets



There are no related publications available for this product.


RESEARCH AREAS

Inflammation, Ser/Thr Kinases



SIGNALCHEM BIOTECH INC.


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