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CAMK2 gamma, Active

Recombinant human CAMK2gamma (c-terminal truncation) was expressed by baculovirus in Sf9 cells using an N-terminal GST tag.
Catalog No. C14-10G


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Catalog No. Pack Size Price (USD)
C14-10G-05 5 ug $226
C14-10G-10 10 ug $325
C14-10G-BULK BULK Contact Us  


Overview:

CAMK2γ is a member of the CAMKII family which are ubiquitous serine/threonine protein kinases that have been implicated in diverse effects of hormones and neurotransmitters. CAMK2γ has six alternatively spliced variants that encode six different isoforms. Some of these variants have been identified in human tumors (1). Transgenic mice expressing a partially calcium-independent mutant form of CAMKG showed 1.5- to 2-fold increase in the thymus of these mice, at least in part due to an increase in the life span of double-positive thymocytes (2). There was an increase in the number of T cells in the secondary lymphoid organs that had acquired an antigen-dependent memory phenotype.


Gene Aliases:

CAMKG, CAMK, CAMK-II, MGC26678


Genbank Number:


References:


1. Tombes, R. M. et al: Identification of novel human tumor cell-specific CaMK-II variants. Biochim. Biophys. Acta 1355: 281-292, 1997.

2. Bui, J. D. et al: A role for CaMKII in T cell memory. Cell 100: 457-467, 2000.


Specific Activity:

Sample Kinase Activity Plot. For specific information on a given lot, see related technical data sheet.


Purity:

Sample Purity Data. For specific information on a given lot, see related technical data sheet.


Storage, Stability and Shipping:

Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.


Molecular Weight:

~60 kDa



Product Datasheets



RESEARCH AREAS

Cardiovascular Disease, ERK/MAPK Pathway, Neurobiology, PKA/PKC Pathway, Ser/Thr Kinases


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