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SCYL2 Protein

Recombinant human SCYL2 (1-520) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Catalog No. S03-35G


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Catalog No. Pack Size Price (USD)
S03-35G-20 20 ug $215
S03-35G-50 50 ug $435
S03-35G-BULK BULK Contact Us  


Overview:

SCYL2 or SCY1-like 2 (S. cerevisiae) is an evolutionarily conserved protein involved in SNARE sorting that is essential for normal embryonic development (1). SCYL2 serves as a regulatory factor for Vpu (viral protein U) which reducing the extent of Vpu phosphorylation and consequently enhancing BST2-mediated viral restriction (2).


Gene Aliases:

CVAK104, KIAA1360


Genbank Number:


References:


1. Borner GH. et.al: CVAK104 is a novel regulator of clathrin-mediated SNARE sorting. Traffic. 2007 Jul;8(7):893-903.

2. Miyakawa K. et.al: Interferon-induced SCYL2 limits release of HIV-1 by triggering PP2A-mediated dephosphorylation of the viral protein Vpu. Sci Signal. 2012 Oct 9;5(245):ra73. doi: 10.1126/scisignal.2003212


Purity:

Sample Purity Data. For specific information on a given lot, see related technical data sheet.


Storage, Stability and Shipping:

Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.


Molecular Weight:

~84 kDa



Product Datasheets



There are no related publications available for this product.


RESEARCH AREAS

Inflammation, Invasion/Metastasis, Neurobiology


RELATED PRODUCTS


  SCYL1 Protein, S04-35G

  SCYL3 Protein, S09-30G


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