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CDK20 (CCRK) Protein

Full-length recombinant mouse CDK20 (CCRK) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Catalog No. C21-30G


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Catalog No. Pack Size Price (USD)
C21-30G-20 20 ug $215
C21-30G-50 50 ug $435
C21-30G-BULK BULK Contact Us  


Overview:

CDK20 or cyclin-dependent kinase 20 contains a kinase domain most closely related to the cyclin-dependent protein kinases which may activate cyclin-dependent kinase 2 and is involved in cell growth. CDK20 is a monomeric CAK that specifically phosphorylates CDK2 thr160 and functions as a CDK2-activating kinase. CDK20 is also a novel cyclin-dependent kinase-activating kinase in mammalian cells (1). CDK20 depletion inhibits glioblastoma cell proliferation in a cilium-dependent manner (2).


Gene Aliases:

CCRK; CDCH; PNQLARE; p42; MGC38901


Genbank Number:


References:


1. Liu, Y.et.al: p42, a novel cyclin-dependent kinase-activating kinase in mammalian cells. J. Biol. Chem. 279: 4507-4514, 2004.

2. Yang Y. et.al: CRK depletion inhibits glioblastoma cell proliferation in a cilium-dependent manner. EMBO Rep. 2013 Aug;14(8):741-7


Purity:

Sample Purity Data. For specific information on a given lot, see related technical data sheet.


Storage, Stability and Shipping:

Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.


Molecular Weight:

~64 kDa



Product Datasheets



RESEARCH AREAS

Cancer, Cell Cycle, Ser/Thr Kinases


RELATED PRODUCTS


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  CDK7/CyclinH1/MNAT1, Active, C36-10H


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