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Anti-phospho-Tau (Ser214)

Rabbit Polyclonal Antibody
Catalog No. T08-365GR




Catalog No. Pack Size Price (USD)
T08-365GR-100 100 ug $248
T08-365GR-BULK BULK Contact Us  


References:


1. Smet C, et al: Regulation of Pin1 peptidyl-prolyl cis/trans isomerase activity by its WW binding module on a multi-phosphorylated peptide of Tau protein. FEBS Lett. 2005 Aug 1;579(19):4159-64.

2.Puig B, et al: Individual and regional variations of phospho-tau species in progressive supranuclear palsy. Acta Neuropathol. 2005 Sep;110(3):261-8.

3. Götz J, et al: Formation of neurofibrillary tangles in P301l tau transgenic mice induced by Abeta 42 fibrils. Science. 2001 Aug 24;293(5534):1491-5.

4. Illenberger S, et al: The endogenous and cell cycle-dependent phosphorylation of tau protein in living cells: implications for Alzheimer's disease. Mol Biol Cell. 1998 Jun;9(6):1495-512.


Specificity:

Recognizes endogenous levels of Tau only when phosphorylated at serine 214


Cross Reactivity:

Human, Mouse and Rat


Host:

Rabbit, IgG


Immunogen:

The antiserum was produced against synthesized phosphopeptide derived from human Tau around the phosphorylation site of serine 235 (P-K-SP-P-S)


Purification:

Affinity chromatography


Stability:

Store at 4oC (add 0.1% NaN3) for several months, and at -20oC for longer periods. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.


Sample Data:

Western blot analysis of extract from mouse brain tissue using Anti-phospho-Tau (Ser214) antibody



Product Datasheets



RESEARCH AREAS

Invasion/Metastasis, Neurobiology, p38 Pathway



SIGNALCHEM BIOTECH INC.


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