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Anti-phospho-Tau (Ser235)

Rabbit Polyclonal Antibody
Catalog No. T08-365FR




Catalog No. Pack Size Price (USD)
T08-365FR-100 100 ug $248
T08-365FR-BULK BULK Contact Us  


References:


1. Alonso Adel C, et al: Promotion of hyperphosphorylation by frontotemporal dementia tau mutations. J Biol Chem. 2004 Aug 13;279(33):34873-81.

2. Liu F, et al: Involvement of aberrant glycosylation in phosphorylation of tau by cdk5 and GSK-3beta. FEBS Lett. 2002 Oct 23;530(1-3):209-14.

3. Sengupta A, et al: Phosphorylation of tau at both Thr 231 and Ser 262 is required for maximal inhibition of its binding to microtubules. Arch Biochem Biophys. 1998 Sep 15;357(2):299-309.

4. Kyriakis JM, et al: The stress-activated protein kinase subfamily of c-Jun kinases. Nature. 1994 May 12;369(6476):156-60.


Specificity:

Recognizes endogenous levels of Tau only when phosphorylated at serine 235


Cross Reactivity:

Human, Mouse and Rat


Host / Isotype / Clone#:

Rabbit, IgG


Immunogen:

The antiserum was produced against synthesized phosphopeptide derived from human Tau around the phosphorylation site of serine 235 (P-K-SP-P-S)


Purification:

Affinity chromatography


Stability:

Store at 4oC (add 0.1% NaN3) for several months, and at -20oC for longer periods. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.


Sample Data:

Western blot analysis of extract from mouse brain tissue using Anti-phospho-Tau (Ser235) antibody



Product Datasheets



RESEARCH AREAS

Invasion/Metastasis, Neurobiology, p38 Pathway



SIGNALCHEM BIOTECH INC.


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