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TRIM37, Active

Recombinant full-length human TRIM37 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Catalog No. T292-380G


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Catalog No. Pack Size Price (USD)
T292-380G-20 20 ug $215
T292-380G-50 50 ug $435
T292-380G-BULK BULK Contact Us  


Overview:

TRIM37 or tripartite motif containing 37 is a member of the tripartite motif (TRIM) family whose members are involved in diverse cellular functions such as developmental patterning and oncogenesis. The TRIM motif includes zinc-binding domains, a RING finger region, a B-box motif and a coiled-coil domain. The RING finger and B-box domains chelate zinc and might be involved in protein-protein and/or protein-nucleic acid interactions. Mutations in TRIM37 are associated with mulibrey (muscle-liver-brain-eye) nanism, an autosomal recessive disorder that involves several tissues of mesodermal origin.


Gene Aliases:

MUL; POB1; TEF3


Genbank Number:


References:


1. Avela, K. et al: Gene encoding a new RING-B-box-coiled-coil protein is mutated in mulibrey nanism. Nature Genet. 25: 298-301, 2000

2. Kallijarvi, J. et al: The TRIM37 gene encodes a peroxisomal RING-B-box-coiled-coil protein: classification of mulibrey nanism as a new peroxisomal disorder. Am. J. Hum. Genet. 70: 1215-1228, 2002


Specific Activity:

Sample Activity Plot. For specific information on a given lot, see related technical data sheet.


Purity:

Sample Purity Data. For specific information on a given lot, see related technical data sheet.


Storage, Stability, and Shipping:

Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.


Molecular Weight:

140 kDa



Product Datasheets



Safety Datasheet



There are no related publications available for this product.


RESEARCH AREAS

Cancer, Metabolic Disorder


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