Full-length recombinant human MEP50 (WDR77) protein was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Catalog No. W329-30G
Catalog No. | Pack Size | Price (USD) | |
---|---|---|---|
W329-30G-20 | 20 ug | $314 | |
W329-30G-50 | 50 ug | $545 | |
W329-30G-BULK | BULK | Contact Us |
Overview:
Methylosome protein 50 (MEP50) is a component of methylosome that contains the methyltransferase JBP1 (PRMT5) and the pICln protein. The methylosome functions to modify specific arginines to dimethylarginines in the arginine- and glycine-rich domains of several spliceosomal Sm proteins. Within the methylosome, MEP50 binds protein substrates and activates the oncogenic protein arginine methyl transferase 5 (PRMT5).
Gene Aliases:
WDR77, HKMT1069, MGC2722, Nbla10071, RP11-552M11.3
Genbank Number:
References:
1. Zilka, N., et al. Truncated tau from sporadic Alzheimer's disease suffices to drive neurofibrillary degeneration in vivo. FEBS Lett. 2006; 508: 3582-3588.
2. Rial, A. et al: Calcium Dyshomeostasis in β-Amyloid and Tau-bearing Skeletal Myotubes. J. Biol. Chem., 2004; 279: 3524-53532
Purity:
Sample Purity Data. For specific information on a given lot, see related technical data sheet.
Storage, Stability, and Shipping :
Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Molecular Weight:
68 kDa
There are no related publications available for this product.
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