DPY30 Protein
Recombinant full-length human DPY30 was expressed in E.coli cells using an N-terminal His tag.
Catalog No. D369-30H
| Catalog No. | Pack Size | Price (USD) | |
|---|---|---|---|
| D369-30H-20 | 20 ug | $215 | |
| D369-30H-50 | 50 ug | $435 | |
| D369-30H-BULK | BULK | Contact Us |
Recombinant full-length human DPY30 was expressed in E.coli cells using an N-terminal His tag.
Catalog No. D369-30H
| Catalog No. | Pack Size | Price (USD) | |
|---|---|---|---|
| D369-30H-20 | 20 ug | $215 | |
| D369-30H-50 | 50 ug | $435 | |
| D369-30H-BULK | BULK | Contact Us |
Overview:
As a core subunit of the SET1/MLL histone methyl-transferase complexes, DPY30 modulates H3K4 methylation in vitro, and directly regulates chromosomal H3K4 trimethylation (H3K4me3) throughout the mam-malian genome. The methylation event has been shown to affect embryonic stem cells (ESCs) maintenance and differentiation. Depletion of Dpy-30 does not affect ESC self-renewal, but significantly alters the differentiation potential of ESCs, particularly along the neural lineage.
Gene Aliases:
Cps25; HDPY-30; Saf19
Genbank Number:
References:
1. Zilka, N., et al. Truncated tau from sporadic Alzheimer's disease suffices to drive neurofibrillary degeneration in vivo. FEBS Lett. 2006; 508: 3582-3588.
2. Rial, A. et al: Calcium Dyshomeostasis in β-Amyloid and Tau-bearing Skeletal Myotubes. J. Biol. Chem., 2004; 279: 3524-53532
Purity:
Sample Purity Data. For specific information on a given lot, see related technical data sheet.
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Storage, Stability, and Shipping:
Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Molecular Weight:
20 kDa
There are no related publications available for this product.
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