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KDM5C Protein

Recombinant human KDM5C (1-671) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Catalog No. K425-31CG


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Catalog No. Pack Size Price (USD)
K425-31CG-20 20 ug $215
K425-31CG-50 50 ug $435
K425-31CG-BULK BULK Contact Us  


Overview:

KDM5C or lysine (K)-specific demethylase 5C is a member of the SMCY homolog family that encodes a protein with one ARID domain, one JmjC domain, one JmjN domain and two PHD-type zinc fingers. KDM5C is mainly expressed in brain and skeletal muscle. KDM5C is involved in the regulation of transcription and chromatin remodelling that cause X-linked mental retardation (1). KDM5C is also essential for spermatogenesis and expression of male-specific minor histocompatibility antigens (2).


Gene Aliases:

JARID1C; DXS1272E; MRXJ; MRXSJ; XE169


Genbank Number:


References:


1. Jensen, L. R. et.al: Mutations in the JARID1C gene, which is involved in transcriptional regulation and chromatin remodeling, cause X-linked mental retardation. Am. J. Hum. Genet. 76: 227-236, 2005.

2. Agulnik, A. I. et.al: A mouse Y chromosome gene encoded by a region essential for spermatogenesis and expression of male-specific minor histocompatibility antigens. Hum. Molec. Genet. 3: 873-878, 1994.


Purity:

Sample Purity Data. For specific information on a given lot, see related technical data sheet.


Storage, Stability and Shipping:

Store product at -70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.


Molecular Weight:

~118 kDa



Product Datasheets



There are no related publications available for this product.


RESEARCH AREAS

Cancer, Cell Cycle, Inflammation


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  KDM5B Protein, K425-31BG


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