Home   >    Proteins   >   Signaling Proteins

STAT2 Protein

Recombinant full-length human STAT2 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Catalog No. S53-54G


Shop Online



Catalog No. Pack Size Price (USD)
S53-54G-50 50 ug $435
S53-54G-20 20 ug $215
S53-54G-BULK BULK Contact Us  


Overview:

STAT2 (Signal transducer and activator of transcription) is a family member of STAT transcription factors that are implicated in programming gene expression in biological events as diverse as embryonic development, programmed cell death, organogenesis, innate immunity, adaptive immunity and cell growth regulation (1). JAKs can phosphorylate and activate STATs. Activation of the JAK/STAT pathway in response to cytokine action can lead to regulation of gene expression during proliferation and differentiation of the immune cells. STATs have been shown to be involved in inflammation, autoimmune and allergic diseases (2).


Gene Aliases:

STAT113, ISGF-3, MGC59816, P113


Genbank Number:


References:


1. Horvath, C.M.: STAT proteins and transcriptional responses to extracellular signals. Trends Biochem Sci. 2000 Oct;25(10):496-502.

2. Pfitzner, E. et al: The role of STATs in inflammation and inflammatory diseases. Curr Pharm Des. 2004;10(23):2839-50.


Purity:

Sample Purity Data. For specific information on a given lot, see related technical data sheet.


Storage, Stability and Shipping:

Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.


Molecular Weight:

~138 kDa



Product Datasheets



There are no related publications available for this product.


RESEARCH AREAS

Apoptosis/Autophagy, Cancer, ERK/MAPK Pathway, Inflammation, JAK/STAT Pathway


RELATED PRODUCTS


  SRC, Active, S19-10G

  STAT3 Protein, S54-54G

  STAT5B Protein, S56-54BH

  STAT3 Protein, S54-54BH


SIGNALCHEM BIOTECH INC.


About

Terms of Service

Privacy Policy

Get the latest resources, updates and offers in your inbox