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STAT1 beta Protein

Recombinant full-length human STAT1beta was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Catalog No. S52-54G


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Catalog No. Pack Size Price (USD)
S52-54G-50 50 ug $435
S52-54G-20 20 ug $215
S52-54G-BULK BULK Contact Us  


Overview:

STAT1β is a member of the signal transducers and activators of transcription (STAT) family of proteins that carry out a dual function: signal transduction and activation of transcription. STAT1β transcription factor is specific for the IFN pathway and plays a central role in mediating many, if not all, IFN-dependent biological responses (1). Presence of STAT1β leads to an efficient antiviral response when cells were infected with virus suggesting that a STAT-dependent pathway is activated following virus infection by endogenously produced IFN. Virus-induced STAT protein translocation from the cytoplasmic compartment can be detected within 3 h of infection.


Gene Aliases:

ISGF-3; STAT91; DKFZp686B04100


Genbank Number:


References:


1. Improta, T. et al: Susceptibility to virus infection is determined by a Stat-mediated response to the autocrine effect of virus-induced type I interferon. Cytokine. 1997 Jun;9(6):383-93.


Purity:

Sample Purity Data. For specific information on a given lot, see related technical data sheet.


Storage, Stability and Shipping:

Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.


Molecular Weight:

~118 kDa



Product Datasheets



RESEARCH AREAS

Apoptosis/Autophagy, Cancer, ERK/MAPK Pathway, Inflammation, JAK/STAT Pathway


RELATED PRODUCTS


  STAT2 Protein, S53-54G

  STAT5 Protein, S56-54H

  Anti-STAT3, S54-63R

  STAT6 Protein, S57-30G


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