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Tau-316 Protein

Recombinant full-length human tag-free Tau-316 was expressed in E. coli cells.
Catalog No. T02-54N


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Catalog No. Pack Size Price (USD)
T02-54N-20 20 ug $160
T02-54N-50 50 ug $336
T02-54N-BULK BULK Contact Us  


Overview:

Tau-316 encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. Tau-316 transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type (1). Tau-316 gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy (2).


Gene Aliases:

Fetal-tau, Tau-A, TAU; MAPT, MSTD; PPND; DDPAC; MAPTL; MTBT1; MTBT2; FTDP-17


Genbank Number:


References:


1. Brown, J.et.al: Familial dementia with swollen achromatic neurons and corticobasal inclusion bodies: a clinical and pathological study. J. Neurol. Sci. 135: 21-30, 1996.

2. Alonso, A. D. C. et.al: Alzheimer's disease hyperphosphorylated tau sequesters normal tau into tangles of filaments and disassembles microtubules. Nature Med. 2: 783-787, 1996.


Purity:

Sample Purity Data. For specific information on a given lot, see related technical data sheet.


Tau Proteins:

Representation of seven Tau proteins, from top to bottom: Tau-441, Tau-410, Tau-412, Tau-381, Tau-383, Tau-352 and Tau-316 (Tau Protein Marker; Cat # T08-07N).


Storage, Stability and Shipping:

Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.


Molecular Weight:

~39 kDa (32.9kDa by MW calculation)



Product Datasheets



RESEARCH AREAS

Invasion/Metastasis, Neurobiology, p38 Pathway


RELATED PRODUCTS


  Tau-441 (151-421) Protein, T08-55EN

  Tau-441 (50-441) Protein, T08-55MN

  Tau-441 (1-421) Protein, T08-55BN

  Tau-441, PHKG2-phosphorylated, T08-50KN


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