Recombinant human TAF1 (1-561) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Catalog No. T28-35G
| Catalog No. | Pack Size | Price (USD) | |
|---|---|---|---|
| T28-35G-20 | 20 ug | $215 | |
| T28-35G-50 | 50 ug | $435 | |
| T28-35G-BULK | BULK | Contact Us |
Overview:
TAF1 is a DNA-binding protein complex required for RNA polymerase II-mediated transcription of many, if not all, protein-encoding genes in eukaryotic cells. TAF1 plays a key role in the initiation process, since it binds to the TATA element to form a complex that nucleates the assembly of the other components into a preinitiation complex and that may be stable through multiple rounds of transcription. TAF1 may be targeted to specific chromatin-bound promoters and may play a key role in chromatin recognition (1). TAF1 also serves to link the control of transcription to the cell cycle (2).
Gene Aliases:
BA2R; CCG1; CCGS; DYT3; DYT3/TAF1; KAT4; N-TAF1; NSCL2; OF; P250; TAF2A
Genbank Number:
References:
1. Jacobson, R. H. et.al: Structure and function of a human TAFII250 double bromodomain module. Science 288: 1422-1425, 2000.
2. Starr, D. B. et.al: TFIID binds in the minor groove of the TATA box. Cell 67: 1231-1240, 1991.
Purity:
Sample Purity Data. For specific information on a given lot, see related technical data sheet.
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Storage, Stability and Shipping:
Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Molecular Weight:
~130 kDa
There are no related publications available for this product.
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